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- 1NFL Week 5 picks: Cowboys and 49ers favored●NFL Week 5 picks and predictions, straight-up and ATS: Cowboys win big, 49ers stay hot
Week 5 of the NFL season is underway, and FanSided has released its full slate of picks and predictions, both straight-up and against the spread. The outlet is calling for the Dallas Cowboys to win big and the San Francisco 49ers to keep their winning streak going. Fans are weighing in on the picks as the week's matchups unfold across the league.