search
cancer research
Trends
- 113-Year-Old Reported Cured of Deadly Brain Cancer DIPG●A 13-Year-Old Has Been Cured of DIPG, the Deadliest Childhood Brain Cancer
A 13-year-old has reportedly become the first patient cured of DIPG, an aggressive and almost universally fatal childhood brain cancer. The announcement, described as a world first, is drawing attention because DIPG has resisted decades of treatment efforts, with most children diagnosed surviving less than a year. If confirmed, it could mark a turning point in pediatric cancer research.
- 2AstraZeneca invests $2bn in cancer drug partnership with Summit Therapeutics●📈 Astrazeneca invests $2bn in cancer drug tie-up Astrazeneca has invested $2bn in US pharmaceutical firm Summit Therapeu
AstraZeneca has invested $2bn in US biotech firm Summit Therapeutics as part of a major cancer research collaboration. The FTSE 100 drugmaker agreed to buy 109,000 shares in the Nasdaq-listed company at $18.36 per share, funding a tie-up aimed at developing new cancer treatments.
- 3Proliferative Pause Offers Window to Prevent Brain Metastasis●Proliferative Pause Reveals Window to Prevent Brain Metastasis
Researchers report that cancer cells entering a 'proliferative pause' — a dormant, slow-dividing state — may expose a critical window during which brain metastasis could be prevented. The finding suggests that targeting cells during this quiescent phase, before they resume growth in the brain, could open new preventive strategies against one of the deadliest consequences of cancer spread.
- 4p53 shown to prevent chromothripsis by balancing transcription and replication●p53 keeps a transcription–replication balance that prevents chromothripsis
Research published in Nature reports that the p53 tumour suppressor protein maintains a balance between transcription and DNA replication, and that this balance prevents chromothripsis, a catastrophic form of chromosome shattering linked to cancer. The finding adds to understanding of how p53 suppresses tumours beyond its established roles in cell-cycle control and apoptosis, and highlights genome instability mechanisms relevant to cancer research.