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    Record Store Day has announced the titles for its RSD Black Friday 2026 event, with exclusive releases from Iron Maiden, Kreator, Mötley Crüe, Carcass, Motörhead, Rainbow and Skid Row among the offerings. The annual November spin-off gives collectors a second wave of limited-edition vinyl, and fans are combing the list for rare pressings.

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    Study links UCHL5 protein to osteoarthritis cell death pathway●UCHL5 stabilizes ALK5 to promote autophagy dependent ferroptosis in osteoarthritis✉newsScienceBiology1 h ago

    Researchers report in Nature that the enzyme UCHL5 stabilizes ALK5, a receptor involved in cell signaling, thereby promoting autophagy-dependent ferroptosis in osteoarthritis. The findings shed light on how iron-dependent cell death contributes to cartilage degeneration, and suggest UCHL5 and ALK5 as potential therapeutic targets for treating the joint disease.

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    Primitive Technology Tries Three Iron Consolidation Experiments●Primitive Technology: 3 Iron Consolidation Experiments▶youtubeTechnology1.7M1 h ago

    The Primitive Technology channel has released a new video showing three experiments in consolidating iron, continuing its trademark format of building and smelting using only primitive tools and materials. The upload is drawing heavy attention, with engagement approaching two million, as viewers follow the creator's long-running project of producing metal from raw ore without modern equipment.

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    Brazilian personality Michelle Barros responded to online criticism about her appearance with a sarcastic message aimed at internet 'haters'. In the note, she wished those commenting on her looks an incredible day, a remark widely read as ironic. The response has drawn attention in Brazilian entertainment coverage, with reactions divided between support for her attitude and continued debate over appearance-based criticism online.

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    Guardians trail White Sox as 'End of the Road' plays at Rate Field●Cleveland Guardians working out at Rate Field. They trail 2-0. Boyz II Men’s “End of The Road” just happens to be playinMmastodonSportBaseball23 h ago

    The Cleveland Guardians are working out at Rate Field in Chicago while trailing the White Sox 2-0, and Boyz II Men's 'End of the Road' played over the stadium speakers. The ironic timing of the song during a losing effort quickly drew attention from baseball observers following the AL Central matchup.

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    Tories pledge UK 'Iron Dome' missile defence shield▼Tories pledge British Iron Dome🦋bluesky8345 h ago

    The Conservative Party has pledged to build a British version of Israel's Iron Dome, a missile defence shield protecting the UK from aerial attack. The announcement is drawing debate about cost, feasibility and whether such a system suits Britain's defence needs, with critics questioning the comparison to Israel's situation and supporters framing it as a response to growing threats.

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    New Ferritin Thresholds in Guidelines Bring Benefits and Drawbacks●New Ferritin Thresholds Recommended in Guidelines Have Benefits, Disadvantages✉newsHealthMedicine56 min ago

    New clinical guidelines recommend updated ferritin thresholds for diagnosing and managing iron deficiency, a shift that carries both benefits and disadvantages. The change is expected to affect how physicians interpret iron levels, potentially catching more cases of deficiency while also raising concerns about overdiagnosis and unnecessary treatment for some patients.

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    Meme sarcastically denies Israel is an apartheid state●not an apartheid tho #meme #memes #palestine #freepalestine #israelMmastodonWarMiddle East45 h ago

    An ironic meme circulating online mocks claims that Israel's treatment of Palestinians does not constitute apartheid, using the sarcastic framing 'not an apartheid though'. The content aligns with pro-Palestine commentary, alongside hashtags like #freepalestine, amid ongoing debate over Israel's policies in the occupied territories and disputes over whether they meet the legal definition of apartheid.

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    Verstappen wins Bahrain Grand Prix with rule he criticised●Controversial F1 rule criticised by Max Verstappen helped him win Bahrain Grand Prix✉newsSportMotorsport7 h ago

    Max Verstappen won the Bahrain Grand Prix, with the result partly attributed to a Formula 1 rule the Dutch driver had previously criticised. The irony of him benefiting from a regulation he publicly opposed has drawn attention from fans and commentators, reopening debate about whether the rule should stay in the sport.

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    Missouri congresswoman Ann Wagner's reelection campaign released a spot titled 'Very Progressive' as part of her congressional bid. The ad has attracted heavy engagement online, with viewers debating its ironic tone and Wagner's record. The race is being watched as part of the broader contest for control of Congress, fueling discussion across the political spectrum.

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    The World Bank is calling on Guinea to use revenue from its vast iron ore resources, including the giant Simandou deposit, to diversify an economy heavily reliant on mining exports. The advice comes as large-scale iron ore projects move toward production, raising the stakes for how Conakry manages the windfall and invests in other sectors of the economy.

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    Sarcastic Ukrainian post mocks Russian soldiers' lung 'pneumonia'●❗️Дуже специфічна форма пневмонії дісталася вже й до окупантів на фронті. Одразу у трьох росіян чомусь зʼявилися дірки вMmastodonWarUkraine011 h ago

    A Ukrainian commentary claims a 'very specific form of pneumonia' has reached Russian occupying soldiers on the front line, saying three Russians developed holes in their lungs spreading 'by air, or shrapnel'. The message is clearly ironic, describing combat wounds as an airborne illness, and urges supporters to donate to the Rusoriz fundraising effort so the 'disease' keeps advancing against occupying forces.

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    Badenoch denies 'British Iron Dome' plan after Tory press release●Badenoch denies 'British Iron Dome' plan - after Tories use phrase in press release https://www.theguardian.com/politicsMmastodonWorldDefense211 h ago

    Kemi Badenoch has denied that the Conservatives are proposing a 'British Iron Dome' missile defence system, despite the party's own press release using the phrase. The discrepancy between the Tory communication and the leader's denial has drawn attention in UK political coverage, raising questions about the party's defence messaging and internal coordination.