multiomics

Researchers publishing in Nature have used spatially resolved multiomics to map how the human meninges, the protective membranes surrounding the brain and spinal cord, develop. The work traces cell lineages during development and links them to disease dynamics, offering a reference for understanding neurological disorders tied to meningeal biology. It is being discussed among researchers following developmental biology and single-cell genomics.

Researchers report in Nature Chemical Biology a multiomic proximity labeling method for use in living systems, based on a D-amino-acid-activated peroxidase reaction. The approach aims to map biomolecular interactions in vivo across multiple molecular layers, and is drawing attention among researchers interested in improved tools for studying protein environments in living tissue.