platform trials

The first US trial against TikTok is set to test claims that the platform fueled a teen mental health crisis. The case will examine whether the app's design and algorithms contributed to harm among young users, and its outcome could shape the wave of similar lawsuits and regulatory pressure facing social media companies in the United States.

Platform trials, which test multiple treatments against a single control group, are changing how clinical evidence is generated in medicine. Commentators argue that regulators have not yet adapted their standards to this trial design, raising questions about how such evidence will be assessed for drug approvals.