ABCC1-677aa

Researchers report that a circular RNA, CircAbcc1, encodes a protein called ABCC1-677aa that modulates the DLX1 molecule to suppress ferroptosis, an iron-dependent form of cell death, in chronic cerebral ischemia. The finding, published in Nature, points to a previously unknown mechanism that could inform future therapies for reduced blood flow to the brain and the neuronal damage it causes.