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immune cells
Trends
- 1
Health outlets are highlighting an mRNA vaccine being developed for melanoma, the deadliest form of skin cancer. The approach uses the same mRNA technology proven in COVID-19 vaccines, training the immune system to recognize and attack tumor cells. WVU Medicine shared the update, and the item is drawing attention as trials of personalized cancer vaccines continue to advance globally.
- 2Blocking immune cells' entry into brain limits neurodegeneration▼Blocking immune cells’ path into brain limits neurodegeneration
Researchers at Washington University School of Medicine report that blocking the route immune cells use to enter the brain can limit neurodegeneration. The findings suggest a potential therapeutic strategy for diseases like Alzheimer's and other neurodegenerative conditions, by preventing inflammatory immune cells from crossing into brain tissue and damaging neurons.
- 3CAR T cell therapy shows two years free of lupus flares●Two years later, CAR T cell therapy shows promise for life without lupus flares
Researchers at UMass Chan Medical School report that lupus patients treated with CAR T cell therapy have remained free of disease flares two years after receiving the one-time cell-based treatment. The therapy, originally developed for blood cancers, reprograms a patient's own immune cells, and the latest follow-up data suggest it may offer lasting remission in autoimmune disease.
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Researchers report that artificial intelligence can identify signs of aging in blood stem cells by analyzing images of cell nuclei alone, without other biological markers. The finding suggests nuclear appearance carries measurable information about cellular aging. If validated, the approach could offer a simpler way to study blood stem cell aging and age-related declines in the immune and blood systems.
- 5UConn Health Launches CAR-T Cell Therapy Program▼UConn Health Launches Cutting-Edge CAR-T Cell Therapy Program
UConn Health has announced the launch of a new CAR-T cell therapy program, a form of immunotherapy that engineers a patient's own immune cells to fight cancer. The initiative brings an advanced, personalised cancer treatment to the Connecticut institution, expanding access for patients in the region who previously had to travel elsewhere for such therapy.
- 6Vyriad Launches First-in-Human Trial of CAR T Therapy VV169▼Vyriad Begins First-in-Human Trial of In Vivo CAR T Therapy VV169
Biotech company Vyriad has begun the first-in-human clinical trial of VV169, an in vivo CAR T therapy that engineers immune cells inside the patient's body rather than in a lab. The early-stage trial marks a first step in testing the safety of the experimental cancer treatment in people, an approach watched closely as it could simplify a cell therapy process that is currently complex and costly.
- 7Plant-Based Nanoparticles Disarm MRSA Bacteria▼Plant-Powered Nanoparticles Strip MRSA of Its Adhesive Weapons
Researchers have developed plant-derived nanoparticles that can strip MRSA of the adhesive mechanisms the antibiotic-resistant bacterium uses to stick to cells and surfaces. By removing these adhesive weapons, the nanoparticles could make the superbug easier for the immune system to clear, offering a potential alternative approach to treating resistant infections without relying on traditional antibiotics.
- 8CAR-T Therapy Expands From Cancer to Autoimmune Diseases▼Enhancing CAR-T Therapy: From Cancer to Autoimmune Diseases
Researchers at Yale School of Medicine are exploring how CAR-T cell therapy, originally developed to treat blood cancers, could be adapted to treat autoimmune diseases. The approach engineers a patient's immune cells to target disease-causing cells, and scientists are now studying its potential against conditions where the immune system attacks the body itself.