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immune cells
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- 1Long Covid autoantibody study finds no single immune signature▼Some autoantibodies against neuronal targets found in people with # LongCovid but no specific signature....it's heteroge
New findings show that some people with Long Covid carry autoantibodies targeting neuronal cells, but no consistent antibody signature has been identified across patients. Commenters say the picture is heterogeneous, meaning the immune response differs from person to person. Many note this fits expectations that Long Covid and ME/CFS have an autoimmune component without being classic autoimmune diseases like multiple sclerosis.
- 2AI Designs Working T-Cell Receptors for Immunotherapy Screening●AI Designs Working T-Cell Receptors That Could Transform Immunotherapy Screening
Researchers report that artificial intelligence has successfully designed functional T-cell receptors, a breakthrough that could speed up screening for immunotherapies. The AI-generated receptors are said to work in practice, suggesting machine learning can help engineer immune-cell treatments more quickly than traditional lab methods. The development is drawing attention for its potential to accelerate cancer immunotherapy research.
- 3Augusta University researcher details neutrophils' shape-shifting behavior in new review▼IMMCG researcher highlights neutrophils’ ‘chameleon’ behavior in new review
A researcher at Augusta University's IMMCG has published a new review examining how neutrophils, a type of white blood cell, behave like 'chameleons' — adapting their roles in the immune system in ways that complicate research and treatment. The paper gathers current findings on the cells' versatile and sometimes contradictory functions in infection, inflammation and disease.
- 4Ralph Steinman's posthumous 2011 Nobel Prize remembered●Ralph M Steinman, who died OTD in 2011, received the Nobel Prize in 2011 for discoveries in # immunology https:// toilet
Canadian immunologist Ralph M. Steinman, who died on this day in 2011, was awarded the Nobel Prize in Physiology or Medicine that same year for his discovery of dendritic cells and their role in adaptive immunity. His death days before the announcement was unusual, as Nobel rules generally exclude posthumous awards, making his case a rare exception that still draws attention each year.
- 5CAR-T Therapy Expands From Cancer to Autoimmune Diseases▼Enhancing CAR-T Therapy: From Cancer to Autoimmune Diseases
Yale School of Medicine is highlighting advances in CAR-T therapy, a treatment that engineers a patient's immune cells to fight disease. Originally developed for blood cancers, the approach is now being adapted and studied for autoimmune conditions, marking a significant expansion of its potential use in medicine.
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New coverage from Technology Networks examines efforts to design improved agonistic antibodies, drugs that activate immune-cell receptors to help the body attack tumours. The piece outlines how engineering strategies aim to enhance their potency and safety for cancer immunotherapy, a fast-growing field where several agonistic antibody candidates have struggled to show clinical benefit so far.