kinases

Researchers have published a phosphoproteome atlas of human cell lines in Nature, charting the landscape of kinase activity across widely used laboratory models. The resource documents phosphorylation patterns that indicate which kinases are active in different cell lines, offering scientists a reference for studying cell signalling and for selecting appropriate models in cancer and drug research.

A new research release features an image showing light-induced clustering of Aurora A, a protein kinase involved in cell division. The technique uses light to trigger the protein to cluster, allowing researchers to study its behaviour with greater precision. Aurora A is of wide interest in biology because of its role in mitosis and links to cancer research.