kinases

Researchers have published a phosphoproteome atlas of human cell lines in Nature, charting the landscape of kinase activity across a broad set of cell models. The resource links phosphorylation patterns to kinase function and is expected to help researchers study cell signalling and support cancer and drug discovery research using cell line models.

A new research release features an image showing light-induced clustering of Aurora A, a protein kinase involved in cell division. The technique uses light to trigger the protein to cluster, allowing researchers to study its behaviour with greater precision. Aurora A is of wide interest in biology because of its role in mitosis and links to cancer research.