telomeres

Researchers studying fission yeast have identified a new complex in which the RPA protein joins the telomerase enzyme team, shedding light on how chromosome ends are maintained. The finding, reported by Bioengineer.org, adds to understanding of telomere biology, a field closely tied to ageing and cancer research. Details of the study and its wider implications have not been spelled out in the available coverage.

Researchers have assembled a telomere-to-telomere reference genome of Rosa roxburghii, the cili fruit, and shown that triterpenoid biosynthesis genes have diversified in a lineage-specific manner. The complete genome offers a resource for studying the plant's medicinal compounds and could support breeding varieties with enhanced triterpenoid content.

New research indicates that children and young adults with Fontan circulation—a surgical palliation for single-ventricle congenital heart disease—carry shorter telomeres, a cellular marker typically associated with older age. The finding suggests the condition or its physiological burdens may drive premature biological aging in this population, potentially informing long-term monitoring and care strategies for Fontan patients.