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Federica Raguseo presents phenotype-first covalent drug discovery approach
Original: Interesting talk by Federica Raguseo at # CovModDrugDiscov . She talked about a phenotype-first approach to covalent dru
Researcher Federica Raguseo gave a talk at the CovModDrugDiscov conference on a phenotype-first approach to covalent drug discovery, using the enzyme TYMS (thymidylate synthase) as a case study. The work is associated with a recent bioRxiv preprint. Observers in the drug discovery community have highlighted the talk as an interesting example of phenotypic screening guiding the development of covalent inhibitors.
Why now: Scientists in the drug discovery field are discussing a new phenotype-first methodology presented at a specialist conference and backed by a fresh preprint.
Federica RaguseoCovModDrugDiscovTYMSbioRxiv
Evidence
- Interesting talk by Federica Raguseo at # CovModDrugDiscov . She talked about a phenotype-first approach to covalent drug discovery on the example of TYMS. https://www. biorxiv.org/content/10.64898/2 026.06.10.731339v1.abstract # CovalentInhibitor # DrugDiscovery # Chemistry #… · Stephanhacker2@mstdn.science · 2
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