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Goals and Challenges for Senescence Research

A commentary in Nature outlines the goals and challenges facing research into cellular senescence, the process by which cells stop dividing and accumulate with ageing. Senescence has become a major focus of ageing and cancer research, but the field still faces open questions about how senescent cells are defined, measured, and targeted therapeutically. The piece sets an agenda for what scientists hope to resolve next.

Why now: Ageing biology and potential senolytic therapies are a fast-growing research area with significant medical interest.

Naturecellular senescence

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