✉news ScienceBiology first seen 16 h ago, last 3 h ago, peak #25
Histidine Clusters Explain How Heat and pH Activate Sperm Channel CatSper
Original: Histidine Clusters Reveal How Heat and pH Switch On the Sperm Channel CatSper
Researchers report that clusters of histidine amino acids in the CatSper channel allow sperm to respond to heat and pH changes, helping explain how the ion channel that controls sperm swimming is switched on. The finding sheds light on a key step in fertilization and could inform future research into male fertility.
Why now: New research offers a molecular explanation for how the sperm-specific CatSper channel is activated by temperature and pH.
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