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Study Finds Liver and Brain Pathways Behind Metabolic Disorder Symptoms
Original: Study Reveals Both Liver and Brain Pathways in Differing Symptoms of Inherited Metabolic Disorder
Researchers at Johns Hopkins Medicine report that an inherited metabolic disorder produces its differing symptoms through two distinct biological pathways, one in the liver and one in the brain. The findings suggest the condition's varied effects on patients cannot be explained by a single mechanism, and could point toward more targeted treatments addressing each pathway separately.
Why now: The new Johns Hopkins study offers a fresh explanation for why patients with the same inherited disorder show very different symptoms.
Evidence
- Study Reveals Both Liver and Brain Pathways in Differing Symptoms of Inherited Metabolic Disorder · Johns Hopkins Medicine
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