✉news ScienceBiology first seen 3 d ago, last 3 d ago, peak #19
Evolution of Estrogen Receptors Explains Species' Different Chemical Responses
Original: Evolution of Estrogen Receptors Explains Why Species Respond Differently to Chemicals
Researchers report that the evolutionary divergence of estrogen receptors explains why different species react differently to chemicals, including endocrine-disrupting compounds. Because receptor proteins changed over millions of years, a substance that mimics estrogen in one animal may have little or no effect in another. The finding matters for toxicology and chemical safety testing, since results from model organisms cannot always be assumed to apply to humans.
Why now: It offers a scientific explanation for a long-standing problem in toxicology: why chemical safety results in animals do not always transfer to humans.
estrogen receptorsendocrine-disrupting chemicalstoxicology
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Evidence
- Evolution of Estrogen Receptors Explains Why Species Respond Differently to Chemicals · Bioengineer.org
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