✉news ScienceBiology first seen 5 d ago, last 5 d ago, peak #19
PUS7 enzyme found to steer human stem cell reprogramming
Original: PUS7 pseudouridylation of 7SK orchestrates human somatic cell reprogramming into iPS cells
Researchers report in Nature that the enzyme PUS7 adds pseudouridine modifications to the 7SK RNA, a step that helps orchestrate the reprogramming of human somatic cells into induced pluripotent stem (iPS) cells. The finding highlights RNA modification as a control point in pluripotency and could inform regenerative medicine research.
Why now: A new Nature study links an RNA-modifying enzyme to the efficiency of iPS cell reprogramming, a key topic in stem cell science.
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