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Y chromosome loss found recurrently disrupted in cancers

Original: Recurrent deletions and regulatory disruption of the Y chromosome in cancer

Researchers have documented recurrent deletions and regulatory disruption of the Y chromosome across cancer types, according to a study published in Nature. The work suggests loss or alteration of Y chromosome genetic material may play a functional role in tumour development rather than being incidental, opening questions about how such changes influence cancer biology and potential sex-based differences in disease.

Why now: A new Nature study highlights the Y chromosome's role in cancer, a topic of growing interest in tumour genetics

Y chromosomeNaturecancer research

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