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Nature reviews molecular mechanisms of NLR inflammasome activation
Original: Molecular mechanisms of NLR proteins in inflammasome activation
A Nature review examines how NLR proteins drive inflammasome activation, laying out the molecular steps by which these intracellular immune sensors detect threats and assemble inflammasome complexes that trigger inflammatory responses. The piece consolidates current understanding of NLR signalling and its relevance to inflammatory disease research.
Why now: Ongoing interest in innate immunity research and inflammasome-linked inflammatory diseases keeps this review timely.
NatureNLR proteinsinflammasome
Evidence
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