✉news ScienceBiology first seen 1 d ago, last 1 d ago, peak #18
Scientists reveal structure of Norrin signaling complex
Original: Architecture of the Norrin signaling complex and structure-guided surrogate design
A study published in Nature describes the architecture of the Norrin signaling complex and uses that structural information to guide the design of molecular surrogates. Norrin is a signaling protein involved in retinal blood vessel development, and defects in its pathway are linked to inherited eye disease. Researchers say the structural blueprint could support new therapeutic approaches.
Why now: New structural biology findings with potential implications for treating retinal disease
Evidence
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