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New synthetic lethal drug targets microsatellite instability cancers
Original: A synthetic lethal drug for microsatellite instability cancers
Researchers have reported the development of a synthetic lethal drug aimed at cancers with microsatellite instability, a genetic feature found in colorectal and other tumor types. Synthetic lethality exploits mutations unique to cancer cells, sparing healthy tissue. The work was published in Nature, and scientists say such drugs could expand treatment options for patients whose tumors resist existing immunotherapies.
Why now: A new Nature publication on a promising cancer therapy approach is drawing scientific and medical attention.
Naturemicrosatellite instability cancers
Evidence
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