✉news ScienceBiology first seen 3 d ago, last 3 d ago, peak #12
Cohesin shown to keep active genome domains separate in living cells
Original: Cohesin keeps compact active genome domains from mixing in living cells
New research indicates that cohesin, a protein complex best known for holding chromosomes together, also keeps compact active regions of the genome from mixing inside living cells. The finding clarifies how cells maintain the spatial organisation of their DNA, with implications for understanding gene regulation and what goes wrong in disease when genome architecture breaks down.
Why now: It is a new scientific finding about a fundamental mechanism of genome organisation, attracting attention from the biology community.
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Evidence
- Cohesin keeps compact active genome domains from mixing in living cells · Bioengineer.org
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