✉news ScienceBiology first seen 1 d ago, last 1 d ago, peak #3
UCP1 Expression Boosts NK Cells Against Tumors
Original: Forced expression of UCP1 counteracts the compromised activity of NK cells in the tumor microenvironment
Researchers report that forced expression of UCP1 in natural killer cells can counteract the loss of antitumor activity these immune cells suffer in the tumor microenvironment. The finding, published in Nature, suggests a potential strategy to restore NK-cell function and improve cancer immunotherapy, and is drawing attention from researchers studying tumor immunology and metabolic reprogramming of immune cells.
Why now: A new Nature study points to a metabolic approach for reviving immune cells that tumors suppress, which is relevant to cancer immunotherapy research.
UCP1natural killer cellsNaturetumor microenvironment
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