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Insilico Medicine reports 40% response rate for AI-designed cancer drug

Original: Insilico Medicine Reports 40% ORR at 130 mg for Pan-TEAD Inhibitor ISM6331 Designed Using Generative AI in Heavily Pretreated Mesothelioma at ESMO 2026

Insilico Medicine announced results for ISM6331, a pan-TEAD inhibitor designed using generative AI, at ESMO 2026. In heavily pretreated mesothelioma patients, the drug achieved a 40% objective response rate at the 130 mg dose. The data highlight growing interest in AI-discovered cancer therapies and offer a potential option for patients with limited remaining treatments.

Why now: The ESMO 2026 presentation of strong clinical results for an AI-designed drug is drawing attention from the oncology and biotech communities.

Insilico MedicineISM6331ESMO 2026mesothelioma

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