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Study maps cellular differences in early-onset colorectal cancer

Original: Insights into early-onset colorectal cancer from a single-nucleus RNA-seq atlas of colorectal cancer across the age continuum

Researchers have published a single-nucleus RNA-sequence atlas of colorectal cancer spanning patients of all ages, using it to probe why the disease increasingly strikes younger adults. The work compares tumour cell states across the age continuum and offers molecular clues to early-onset colorectal cancer, a condition rising in under-50s and a growing focus of cancer research worldwide.

Why now: Rising rates of colorectal cancer in younger people have made research into its biological origins a major topic of medical discussion.

Naturecolorectal cancerearly-onset colorectal cancer

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