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✉news ScienceBiology first seen 20 h ago, last 20 h ago, peak #28

Cryo-EM shows how retrotransposons and CRISPR-Cas9 insert genes

Original: Cryo-EM reveals how a retrotransposon and CRISPR–Cas9 team up to insert genes

Researchers have used cryo-electron microscopy to reveal the molecular mechanism by which a retrotransposon works together with CRISPR-Cas9 to insert genes into DNA. The findings offer structural insight into gene-insertion processes, potentially informing the development of more precise gene-editing and gene-therapy tools.

Why now: It combines two hot topics in biology, cryo-EM structural imaging and CRISPR gene editing, with implications for gene-therapy techniques.

CRISPR-Cas9retrotransposoncryo-EM

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