✉news ScienceBiology first seen 1 d ago, last 20 h ago, peak #16
Screen identifies proteins controlling circular RNA metabolism
Original: Large-scale RNA-binding protein tethering screen discovers modulators of circular RNA metabolism
A large-scale RNA-binding protein tethering screen has identified new modulators of circular RNA metabolism, according to a study published in Nature. The approach systematically tethers hundreds of RNA-binding proteins to a target transcript to test how each affects circular RNA formation and turnover. The findings give researchers a map of proteins that regulate circular RNAs, molecules increasingly implicated in gene regulation and disease.
Why now: The study's publication in Nature and its systematic identification of circular RNA regulators make it notable for the molecular biology community.
NatureRNA-binding proteinscircular RNA
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Evidence
- Large-scale RNA-binding protein tethering screen discovers modulators of circular RNA metabolism · Nature
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