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Clues Emerge on Why Pancreatic Cancer Drug Stops Working

Original: Clues to Why a Breakthrough Pancreatic Cancer Drug Eventually Stops Working https://www.nytimes.com/2026/09/30/science/p

New reporting examines why daraxonrasib, a breakthrough drug for pancreatic cancer, eventually stops working in patients. Researchers have identified clues about the resistance mechanisms that develop over time, a step that could guide combination treatments and extend the drug's effectiveness for one of the deadliest cancers.

Why now: Fresh research on drug resistance in a promising pancreatic cancer treatment has drawn attention from clinicians, patients and science readers.

daraxonrasibpancreatic cancerNew York Times

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• Clues to Why a Breakthrough Pancreatic Cancer Drug Eventually Stops Working https://www.nytimes.com/2026/09/30/science/pancreatic-cancer-drug-daraxonrasib-ben-sasse-resistance.html # Science # Health # Medicine · nyt_politics@robot.villas · 2

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