✉news ScienceBiology first seen 3 h ago, last 1 h ago, peak #20
EPR Spectroscopy Seen Closing The Conformation Gap In Drug Research
Original: The Conformation Gap How EPR Unlocks Missing Dynamics In Pharma And Structural Biology Workflow
Bioprocess Online reports on the so-called conformation gap in pharmaceutical and structural biology workflows, arguing that electron paramagnetic resonance (EPR) spectroscopy can reveal protein dynamics that conventional structural methods such as crystallography and cryo-EM miss. The piece suggests adding EPR to drug development pipelines could improve understanding of how target molecules move and change shape, with implications for drug discovery and bioprocess development.
Why now: Interest in new analytical tools that expose protein dynamics beyond static structures is growing across pharma and structural biology.
Bioprocess OnlineEPR spectroscopypharmaceutical industrystructural biology
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Evidence
- The Conformation Gap How EPR Unlocks Missing Dynamics In Pharma And Structural Biology Workflow · Bioprocess Online
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