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NFL Week 4 predictions: 49ers-Broncos and London games

Original: NFL Week 4 odds, predictions, expert picks: Who wins 49ers-Broncos showdown? Colts or Commanders in London?

Week 4 of the NFL season brings a headline matchup between the San Francisco 49ers and Denver Broncos, with oddsmakers and pundits splitting on the winner. Attention also turns to the international series in London, where the Indianapolis Colts face the Washington Commanders. Analysts are publishing picks, betting lines and predictions across Sunday's slate.

Why now: Week 4 matchups, including a marquee 49ers-Broncos game and a London contest, are driving betting and prediction discussion.

San Francisco 49ersDenver BroncosIndianapolis ColtsWashington CommandersNFL

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• NFL Week 4 odds, predictions, expert picks: Who wins 49ers-Broncos showdown? Colts or Commanders in London? · CBS Sports

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