✉news ScienceBiology first seen 4 h ago, last 36 min ago, peak #37
New guidance for selecting adenine base editors in human genome editing
Original: Rational selection of SpCas9 and variant-derived adenine base editors for human genome editing
A study published in Nature presents a rational framework for choosing between SpCas9 and variant-derived adenine base editors when editing the human genome. The work helps researchers match editor choice to specific target sites, improving precision and efficiency of base-editing experiments and supporting safer therapeutic applications.
Why now: Base editing is a fast-moving area of genome medicine, and practical guidance on editor selection is of wide interest to researchers developing therapies.
SpCas9adenine base editorsNature
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Evidence
- Rational selection of SpCas9 and variant-derived adenine base editors for human genome editing · Nature
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