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7SK RNA

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    PUS7 enzyme found to steer human stem cell reprogramming▼PUS7 pseudouridylation of 7SK orchestrates human somatic cell reprogramming into iPS cells✉newsScienceBiology6 d ago

    Researchers report in Nature that the enzyme PUS7 adds pseudouridine modifications to the 7SK RNA, a step that helps orchestrate the reprogramming of human somatic cells into induced pluripotent stem (iPS) cells. The finding highlights RNA modification as a control point in pluripotency and could inform regenerative medicine research.