✉news ScienceScience first seen 8 d ago, last 8 d ago, peak #10
Outside-the-Box Science Sparked a Revolution in Targeting KRAS
Original: A New Way In: How Outside-the-box Science Sparked a Revolution in Targeting KRAS
The American Association for Cancer Research is highlighting how unconventional research approaches led to the first successful drugs targeting KRAS, a cancer-driving protein long considered undruggable. After decades of failure, inhibitors such as sotorasib and adagrasib have now reached patients with KRAS-mutated cancers, marking one of the most significant recent shifts in oncology drug development.
Why now: KRAS inhibitors are a major recent breakthrough in cancer treatment, and the story of how they were achieved is drawing attention from the cancer research community.
American Association for Cancer ResearchKRASsotorasibadagrasib
Rank over time, top of the chart is #1. 3 snapshots from 8 d ago to 8 d ago.
Evidence
- A New Way In: How Outside-the-box Science Sparked a Revolution in Targeting KRAS · American Association for Cancer Research (AACR)
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