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Mmastodon HealthHealth first seen 3 d ago, last 3 d ago, peak #2

Gene map of tuberculosis bacteria could guide new drug combinations

Original: Researchers mapped interactions among 762 genes essential to tuberculosis bacteria and validated several drug synergies.

Researchers have mapped the interactions among 762 genes essential to the tuberculosis bacterium, validating several synergies between drug candidates. The genetic resource is expected to sharpen the search for combination treatments against TB, a disease that still kills over a million people a year. However, most of the findings come from laboratory growth conditions and do not yet prove effective therapies in patients, so further work is needed before clinical use.

Why now: The study offers a potentially valuable tool for developing combination therapies against drug-resistant tuberculosis.

tuberculosisMycobacterium tuberculosisresearchers

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