✉news ScienceBiology first seen 11 h ago, last 55 min ago, peak #18
Self-blinking probes open new view of chromatin
Original: HoT self-blinking probes for chromatin imaging
Researchers report a new class of self-blinking probes, referred to as HoT, that improve fluorescence imaging of chromatin, the complex of DNA and proteins packed inside cell nuclei. By blinking on their own without external activation, the probes allow higher-resolution maps of genome organization. The work is drawing attention in the biology community as a potential tool for studying how genome structure relates to gene activity.
Why now: New imaging chemistry that could reveal chromatin structure at higher resolution is of broad interest to genome and cell biology researchers.
Evidence
- HoT self-blinking probes for chromatin imaging · nature.com
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