✉news ScienceBiology first seen 12 h ago, last 1 h ago, peak #12
New Optimal Transport Framework Reconstructs Gene Networks From Single-Cell Snapshots
Original: New Optimal Transport Framework Reconstructs Gene Networks and Cell Fates From Single-Cell Snapshots
Researchers have introduced a new computational framework based on optimal transport that can reconstruct gene regulatory networks and predict cell fate trajectories from single-cell RNA sequencing snapshots. The method links static measurements of individual cells into dynamic models of development and differentiation. Bioinformatics and computational biology communities are highlighting the approach as a potentially useful tool for studying how cells transition between states over time.
Why now: The framework offers a new mathematical tool for inferring cell dynamics from static single-cell data, an important problem in genomics research.
optimal transportsingle-cell sequencinggene regulatory networks
Rank over time, top of the chart is #1. 9 snapshots from 12 h ago to 1 h ago.
Evidence
- New Optimal Transport Framework Reconstructs Gene Networks and Cell Fates From Single-Cell Snapshots · Bioengineer.org
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