✉news ScienceBiology first seen 17 h ago, last 1 h ago, peak #12
New Optimal Transport Method Reconstructs Cell Fates From Snapshots
Original: New Optimal Transport Framework Reconstructs Gene Networks and Cell Fates From Single-Cell Snapshots
Researchers have introduced a new framework based on optimal transport that can reconstruct gene regulatory networks and predict cell fate trajectories using only static single-cell snapshots. The method infers dynamic processes from static data, allowing scientists to map how cells transition between states and which genes drive those changes. It could advance research in developmental biology, regenerative medicine, and disease modelling.
Why now: The method promises to infer dynamic cellular processes from static single-cell data, a longstanding challenge in computational biology.
optimal transportsingle-cell sequencinggene regulatory networks
Evidence
- New Optimal Transport Framework Reconstructs Gene Networks and Cell Fates From Single-Cell Snapshots · Bioengineer.org
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