✉news ScienceBiology first seen 1 d ago, last 11 h ago, peak #12
New Optimal Transport Method Reconstructs Gene Networks From Single-Cell Data
Original: New Optimal Transport Framework Reconstructs Gene Networks and Cell Fates From Single-Cell Snapshots
Researchers have introduced a new computational framework based on optimal transport that can reconstruct gene regulatory networks and predict cell fates using single-cell snapshot data. The method aims to infer dynamic cellular processes, such as differentiation trajectories, from static measurements of individual cells. The work is being reported in the computational biology and bioinformatics community, where it is seen as a potentially useful tool for studying how cells transition between states.
Why now: The new method offers a way to infer cell dynamics from static single-cell data, a major challenge in genomics
optimal transportsingle-cell sequencinggene regulatory networks
Evidence
- New Optimal Transport Framework Reconstructs Gene Networks and Cell Fates From Single-Cell Snapshots · Bioengineer.org
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