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✉news ScienceBiology first seen 15 h ago, last 4 min ago, peak #12

New Optimal Transport Method Reconstructs Cell Fates From Snapshots

Original: New Optimal Transport Framework Reconstructs Gene Networks and Cell Fates From Single-Cell Snapshots

Researchers have introduced a new framework based on optimal transport that can reconstruct gene regulatory networks and predict cell fate trajectories using only static single-cell snapshots. The method infers dynamic processes from static data, allowing scientists to map how cells transition between states and which genes drive those changes. It could advance research in developmental biology, regenerative medicine, and disease modelling.

Why now: The method promises to infer dynamic cellular processes from static single-cell data, a longstanding challenge in computational biology.

optimal transportsingle-cell sequencinggene regulatory networks

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